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Department of Ophthalmology, Grigore T. E-mail: moc. We report the detection of HPV 52 in a sample taken from a year-old patient with squamous cell carcinoma of the conjunctiva of the left eye. The method used for the detection of HPV was real time polymerase chain reaction.

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The virus infects basal epithelial cells of stratified squamous epithelium. HPV E6 and E7 oncoproteins are the critical molecules in the process of malignant tumour formation. Interacting with various cellular proteins, E6 and E7 influence fundamental cellular functions like cell cycle regulation, telomere maintenance, susceptibility to apoptosis, intercellular adhesion and regulation of immune responses. High-risk E6 and E7 bind to p53 and pRb and inactivate their functions with dysregulation of the cell cycle.

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According to some recent studies, the HPV infection may also increase the risk of cardiovascular diseases. Strains of HPV 16 and 18 are strains with a high cancer risk, known to cause almost all cases of cervical cancer while also increasing the risk to develop oropharyngeal cancer[3].

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Трудно было принять, что снаружи Диаспара вообще есть хоть что-нибудь, но то, что Элвин привел с собой одного из обитателей внешнего мира и собирается представить его мозгу города, было совсем худо. Служители уставились друг на друга в такой беспомощной тревоге, что Элвин с трудом удержался от Пока они шли из парка (причем эскорт держался позади, переговариваясь возбужденным шепотом), Элвин обдумывал следующий ход.

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В течение миллиарда лет информационные схемы сохраняли его призрачное псевдосуществование, ожидая момента, когда кто-нибудь вновь оживит город. И наблюдаемое им, думал Элвин, не просто память.

Это было нечто более сложное - память о памяти.