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Although not-fulfilling all "the Amsterdam  offers  a homogenous but  apparently rigid  frame,  considering  criteria"  for  eligibility  in  the  HNPCC  group,  the  patients  current  molecular  genetics  research. Thus,  more  and  more  with colo-rectal cancer and positive family history showed  patients  that  do  not  fulfil  entirely  those  criteria  and  an  morphoclinical  features  which  suggested  poor  prognosis  important number of patients with sporadic cancers are found  compared to  those with negative family history. A  comparative  analysis  of the  morphoclinical  Key  words  features  in  non-polyposis  colo-rectal  cancer  patients  with  Hereditary  colo-rectal  cancer  -  Amsterdam  Criteria  - positive  family  histories  which  fulfil  entirely  or  partially  prognosis  "the  Amsterdam  criteria"  versus  the  patients  with  sporadic  non-polyposis  colorectal  cancers. Patients  and  methods.

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Although the causes of this disease are not entirely understood, it is known that several factors influence its occurrence. Risk factors for colorectal cancer include age, family history of colon polyps, inflammatory bowel disease cancer sporadic familial hereditary hereditary syndromes, smoking, obesity, sedentarism, alcohol consumption. Evidence is mounting that detecting this risk factors is a eficient way of selecting persons at high risk for colon cancer, that should undergo the screening mesures. Key words: colon cancer, risk factors, colon polyps, inflammatory bowel disease, smoking, obesity, sedentarism, alcohol consumption.

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