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The virus infects basal epithelial cells of stratified squamous epithelium. HPV E6 and E7 oncoproteins are the critical molecules in the process of malignant tumour formation. Interacting with various cellular proteins, E6 and E7 influence fundamental cellular functions like cell cycle regulation, telomere maintenance, susceptibility to apoptosis, intercellular adhesion and regulation of immune responses. High-risk E6 and E7 bind to p53 and pRb and inactivate their functions with dysregulation of the cell cycle.

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Just wanted to share my personal experience with cervical dysplasia and hpv, and hopefully I can help create awareness about the importance of early detection and regular pap smears. I know that this is still a topic not openly discussed because of the stigma of the disease, but I hope from this thread I can reach out to other women out hpv that causes precancerous cells with symptoms but are scared to get a thorough check-up. In during one of my routine pap smears when we were trying to get pregnant, my OB-GYN felt a tiny, tiny lentil-sized lump in my cervix. I have been complaining about abnormal bleeding during intercourse for the past 2 years and ALL my pap smears every 6 months for 3 years!

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According to some recent studies, the HPV infection may also increase the risk of cardiovascular diseases. Strains of HPV 16 and 18 are strains with a high cancer risk, known to cause almost all cases of cervical cancer while also increasing the risk to develop oropharyngeal cancer[3].

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Apasă pentru a vedea definiția originală «human papilloma virus» în dicționarul Engleză dictionary. Apasă pentru a vedea traducerea automată a definiției în Română.

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Олвин видел, что губы ее шевелятся, но слова не долетали до. Он оглянулся на нее сперва удивленно, потом с нетерпением и не без жалости. То, о чем толковал Джизирак, оказалось правдой: Алистра просто не могла следовать за .

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Могу лишь сказать тебе, что он на пути в Лис. Теперь ты знаешь столько же, сколько .

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Алистру давно сбили с толку все эти повороты, но наконец они вышли в длинный, совершенно прямой туннель, в котором с постоянной силой дул холодный ветер. Туннель простирался горизонтально на сотни футов в обоих направлениях, и окончания его представлялись лишь крохотными светлыми кружочками. -- Не нравится мне здесь,-- поежилась Алистра.

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Эти пространства -- Олвин хорошо это понимал -- не были предназначены для Человека. Под пронзительным сиянием голубых огней -- настолько ослепительных, что от них больно было глазам -- длинные и широкие коридоры простирались, казалось, в бесконечность.