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Cancerul mamar in stadiul 4 are loc atunci cand boala intai apare la nivelul sanului, iar apoi metastazeaza sau se raspandeste la alte zone ale corpului. Cele mai frecvente zone pentru metastazele in cancerul mamar sunt ganglionii limfatici, peretele toracic, metastatic cancer nhs, plamanii, ficatul si creierul. Alti termeni folositi pentru aceasta situatie sunt [cancerul de san] "avansat", "metastatic" ori " recidivant ".

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