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Duda's group is focused on studies of tumor interaction with its microenvironment, with the goal of identifying the cellular and molecular mechanisms of: 1 local tumor progression in liver cancers and metastatic tumor progression in other gastrointestinal cancers and in prostate and breast malignanciesand 2 treatment resistance in advanced cancers. The ultimate goal is to identify and validate targets for combination therapy with radiation and immunotherapy in preclinical studies, and in parallel conduct studies of biomarkers of response in correlative clinical studies. He has been invited to present his results at over local, colorectal cancer progression and international meetings, including Grand Rounds, Plenary Talks and Keynote Lectures. For his work, Dr.

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In Romania, the incidence of CRC in is We reviewed a series of studies that are related to colon cancer and studied the epithelial-mesenchymal transition at the front of tumor invasion EMT. Cellular phenotypic changes characteristic of EMT can be induced by the absence of transition cofactor p involved in cellular regulation.

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J Gastrointestin Liver Dis ; 25 3 :Sep. Colorectal cancer progression our knowledge, this study is the first one comparing CHC patients to controls with regard to soft tissue body composition changes. Soft tissue and bone body composition parameters were compared between the groups using the Mann-Whitney test. These parameters were correlated using Spearman's rank correlation coefficient - rho with independent variables age, gender, body mass index - BMI, cigarette smoking, time since CHC diagnosis, viral load, fibrosis grade, type of treatment, time of treatment for the entire Colorectal cancer progression group and also for subgroups according to gender.

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Accepted Apr Copyright © The Authors.

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Tipuri[ modificare modificare sursă ] Un neoplasm poate fi benign, potențial malign sau malign cancer. Sunt circumscrise și localizate, și nu se transformă în cancer. Sunt localizate, nu invadează și nu distrug, dar în timp, se pot transforma într-un cancer.

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