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Aim: To implement the HPV genotyping method of fresh head and neck cancer samples in our laboratory. More than half of the patients recognized being chronic alcohol and tobacco users. Conclusions: The genotyping method was validated according to kit instructions. To get a general idea on the prevalence of HPV genotypes in head and neck cancer in our region we tested a very small number of samples.

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In addition to tobacco and alcohol abuse, certain viruses have been associated with squamous cell carcinoma SCC of the head and neck, causing alterations in DNA. It has been demonstrated that the human papil­loma­virus HPV type 16, a subtype of the human pa­pil­loma­virus, is present in the oropharyngeal carcinomas of non-smokers patients inclusive. HPV-infected cells express some viral proteins encoded by genes called E6 and Hpv tongue surgery, and can inactivate p53 protein and the retinoblastoma-type pro­tein RBP involved in the regulation of proliferation and cell death.

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Frequently, a mandible resection is required in order to obtain safe oncologic margins. The prognosis is good, with a higher overall survival rate than in other oral hpv tongue surgery. Keywords carcinoma, floor of the mouth, mandible resection, neck dissection Rezumat Cu o prevalenţă inferioară tumorilor maligne ale limbii, tu­mo­ri­le maligne de planşeu anterior impun o abordare chi­rur­gi­ca­lă la fel de radicală, cu o margine de siguranţă mare şi cu ma­nage­mentul problemelor de la nivelul gâtului.

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Comentarii Thieme congratulates Dr. Eric M. Genden on being chosen by New York magazine for its prestigious 'Best Doctors ' list!

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Еще не докончив фразы, он каким-то образом уже понял, что говорит что-то неладное. Алистра придушенно вскрикнула, внутренность капсулы как-то странно заколыхалась -- так колышется изображение, рассматриваемое сквозь толщу воды,-- и через металл окружающих его стенок Олвин на краткий миг снова увидел тот, иной мир. Две реальности, похоже, боролись друг с другом -- отчетливее становился то один мир, то.

И затем, совсем внезапно, все кончилось.

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Он разговаривал с Олвином то как со своим товарищем-согражданином, то вдруг вспоминал о долге стража и напускал на себя преувеличенную отчужденность. -- Этот робот, -- произнес он вдруг, указывая на спутника Олвина.

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Он у мониторов, - прозвучал ответ. От этого толку было мало, и Алистра ничего не поняла. Но ни одна машина добровольно не выдавала информации больше, чем у нее просили, а искусству формулирования правильных вопросов нередко приходилось долго обучаться.

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